Even if it’s hidden behind some sort of special input (click both sticks on the menu?), I feel like having the option to, say, use the shoulder buttons to move left/right in-game would be really helpful for one-handed players (and would offer another single Joy-Con play option, especially with the stick there to navigate menus). For left-handed play, that might also require being able to remap D-pad directions to face button stuff, and possibly even assigning special throw/super macros?
Anyway, this is mostly just a thought on a perhaps unorthodox way to add some accessibility.